Health Screening



Human Nailfold Capilary Microcirculation Analysis
            (microcirculation microscopy)


Your blood is kept in continuous motion, flows in a closed circuit from the heart to arteries, arterioles, capillaries, venules (small veins), veins, and then back to the heart. Microcirculation can be considered a “keystone of life” for the delivery and removal of substances in the metabolism of every tissue cell.

When your body doesn’t send enough blood to the hands and feet there may be a problem with blood flow. For the first time in the mid 1800’s this condition of impaired blood circulation and microcirculation was described by a French doctor Maurice Raynaud – the name of Raynaud’s phenomenon – a circulatory disorder in which the blood supply to the hands and feet is reduced.

In normal physiological conditions, the optimal regulation of this process is accomplished through the control of the state of tension of the smooth muscle cells present in the vascular wall, which ultimately determines the maintenance of three different homeostatic processes, namely the maintenance of fluid balance, the delivery of blood to each microscopic domain of the tissues, and the maintenance of the systemic blood pressure.

What is Human Nailfold Capillary Microcirculation Analysis?


Nailfold capillary microcirculation analysis is the analysis of the capillary morphology and microcirculation of the manifold through a special optical microscopy.  Patients with connective tissue diseases including dermatomyositis, scleroderma and systemic lupus erythematosus (SLE) demonstrate changes in the nailfold capillaries. Capillary microscopy allows the changes to be investigated. The nailbed of a finger is painted with liquid paraffin oil, which ensures that the capillaries below the skin surface can be seen. It is then placed under an optical microscopy and the changes of the capillary morphology and microcirculation could be observed.

Following tables shows normal capillary morphological for healthy people, abnormal capillary morphological and possible related diseases



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